WHAT'S THE SCIENCE?
Over Three Decades of Progress in Transdermal Therapy
01 - history
Since the launch of the nicotine patch in 1991, transdermal delivery has become one of the most widely validated technologies in healthcare. Its success proved what’s possible: effective, convenient, and sustained support without the need for pills or powders.
At Lifemaxxing, we’ve taken this proven medical technology and engineered it for everyday wellness—applying the science of skin-based absorption to every core pillar of health.
02 - THE delivery
Most supplements come as pills, gummies, or powders that cause quick spikes, fade fast, and often irritate digestion. Patches work differently:
- Steady Release — Ingredients are delivered gradually for up to 12–24 hours, working in sync with your body’s natural rhythms.
- Bypasses Digestion — Direct absorption through the skin avoids breakdown in the stomach or liver, improving consistency.
- Clinically Backed — Transdermal delivery is validated in controlled studies, showing significant improvements in absorption, stability, and outcomes.
03 - THE STUDIES
Research shows that molecules under 500 Daltons, lipophilic in nature, are ideal for transdermal delivery. Many of the key compounds in our patches—from caffeine to adaptogens—fall squarely within this range.
Our formulas pair these actives with plant-based permeation enhancers to improve absorption and extend release. The result: a delivery system designed for efficacy, comfort, and consistency.
04 - THE RESULTS
Across clinical research and consumer use, transdermal technology has been shown to:
- Improve bioavailability vs. oral supplements
- Provide steadier blood levels of active ingredients
- Reduce digestive irritation and side effects
- Deliver greater convenience and compliance
Lifemaxxing patches aren’t just about avoiding pills—they’re about unlocking smarter, science-backed performance for every health pillar.
CITATIONS
Bos, J. D., & Meinardi, M. M. (2000). The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Experimental Dermatology, 9 (3), 165–169.
Prausnitz, M. R., Mitragotri, S., & Langer, R. (2004). Current status and future potential of transdermal drug delivery. Nature Reviews Drug Discovery, 3, 115–124.
Grammatikopoulou, M. G., et al. (2021).
Peeking into the future: Transdermal patches for the delivery of micronutrient supplements.
Metabolism Open, 11, 100109.
Saurabh, S., Gao, Y., Maduka, S., et al. (2019). Is transdermal multivitamin patch effective in gastric bypass patients? Obesity Surgery, 29 (12), 3818–3823.
Aeschbach, D., Sher, L., Kripke, D. F., et al. (2009). Use of transdermal melatonin delivery to improve sleep maintenance during daytime.
Clinical Pharmacology & Therapeutics, 86 (4), 378–382. researchgate.net
Hamman, J. H., et al. (2011). Transdermal drug delivery enhancement by compounds of natural origin.
International Journal of Molecular Sciences, 12 (4), 784–795. pmc.ncbi.nlm.nih.gov